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Glucose homeostasis is primarily regulated by insulin, which lowers blood glucose by increasing the uptake into cells and increasing its utilization and storage as fat and glycogen in peripheral tissues

Collectively, these observations suggest that the IL-1mediated increases in GSH occur independent from NRF2 or the transsulfuration pathways

Furthermore, Seahorse experiments demonstrated that overexpression of AGXT in HepG2 cells treated with PA significantly enhanced basal respiration, maximal respiration and ATP production compared with GFP control (Fig

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